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Willy Wonka-style lift is a reality

Written By Unknown on Minggu, 30 November 2014 | 22.10

Lamiat Sabin, The Independent | Nov 29, 2014, 07.11AM IST

The "Multi" is engineered to use magnetic force instead of clunky weights and cables, which elevator firm ThyssenKrupp -who announced the development on Thursday-say will save power to help it run more economically.

Page 1 of 4

A lift -which moves sideways as well as vertically much like the one in `Charlie and the Chocolate Factory' -has been designed by a German company .
The " Multi" is engineered to use magnetic force instead of clunky weights and cables, which elevator firm ThyssenKrupp -who announced the development on Thursday-say will save power to help it run more economically .

The characters in Roald Dahl's widely-loved story are "flung off their feet on to the floor" as Willy Wonka's glass elevator moves sideways, whizzes around corners before flying off into the sky.

However, the real-life model can only go up, down and sideways but the company says it will allow multiple lifts to occupy a single shaft to help boost passenger capacity by up to 50%. When a lift reaches the top of a shaft, it will move horizontally before descending via another channel in a "near-constant" loop formation to allow more than one carriage of people to be shuttled around a building.


They also hope the new system which the company claims is the most ground-breaking since the invention of the lift 160 years ago — will help cut waiting time down to around 15 to 30 seconds.

Patrick Bass, head of research and development at ThyssenKrupp, said: "With this technology, the limits (on high-rise structures) will be removed and we will have futuristic buildings that previously could only be dreamed of," according to The Financial Times.

Article continues

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22.10 | 0 komentar | Read More

Using smartphone could be damaging your back: Experts

Looking down at our phones isn't just making us bump into one another, it's also exerting a damaging amount of weight onto the back of heads and necks, says scientists.

How much weight exactly? Twenty seven kilograms is the most recent estimate according to a study published in the journal Surgical Technology International.

That's about the same weight as four full-size bowling balls or - to use a more relevant comparison - 200 iPhones. All piled up on the back of your head.

Dr Kenneth Hansraj, the spinal and orthopaedic surgeon behind the study, says it's become increasingly common for patients suffering from back and neck pain to report hours spent hunched over smartphones and tablets.

"You can call it an epidemic. Wherever you go, just look around: People are heads down into their phones, especially teenagers," Hansraj told NBC news.

The extra pressures is created by weight of the human head and the angle of the neck and spine. The average head weighs around 5kg and this weight increases massively as people hunch over: a sixty degree bend adds an extra 22kg of strain.

"These stresses may lead to early wear, tear, degeneration, and possible surgeries," writes Hansraj.


What texting does to your neck. (Image credit: Surgical Technology International)

Hansraj's advice is simple: be aware of your movements. You don't necessarily have to bring your gadgets up to eye-level to use them, but don't crane over them all the time.

Similarly, try exercises such as touching your ears to your shoulders or pushing your head against your hands, to bring some flexibility and strength back to your neck.

As computing becomes a mobile activity for more and more of us (and that includes slouching on the sofa with a tablet) neck difficulties seem set to join 'texting thumb' in the technology 'hall of pain'. Bring on those brain implants instead.

http://timesofindia.indiatimes.com/followceleb.cms?alias=texting,Spine,Smartphone,Kenneth Hansraj,back pain

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22.10 | 0 komentar | Read More

Using your smartphone could be damaging backs: Experts

Looking down at our phones isn't just making us bump into one another, it's also exerting a damaging amount of weight onto the back of heads and necks, says scientists.

How much weight exactly? Twenty seven kilograms is the most recent estimate according to a study published in the journal Surgical Technology International.

That's about the same weight as four full-size bowling balls or - to use a more relevant comparison - 200 iPhones. All piled up on the back of your head.

Dr Kenneth Hansraj, the spinal and orthopaedic surgeon behind the study, says it's become increasingly common for patients suffering from back and neck pain to report hours spent hunched over smartphones and tablets.

"You can call it an epidemic. Wherever you go, just look around: People are heads down into their phones, especially teenagers," Hansraj told NBC news.

The extra pressures is created by weight of the human head and the angle of the neck and spine. The average head weighs around 5kg and this weight increases massively as people hunch over: a sixty degree bend adds an extra 22kg of strain.

"These stresses may lead to early wear, tear, degeneration, and possible surgeries," writes Hansraj.


What texting does to your neck. (Image credit: Surgical Technology International)

Hansraj's advice is simple: be aware of your movements. You don't necessarily have to bring your gadgets up to eye-level to use them, but don't crane over them all the time.

Similarly, try exercises such as touching your ears to your shoulders or pushing your head against your hands, to bring some flexibility and strength back to your neck.

As computing becomes a mobile activity for more and more of us (and that includes slouching on the sofa with a tablet) neck difficulties seem set to join 'texting thumb' in the technology 'hall of pain'. Bring on those brain implants instead.

http://timesofindia.indiatimes.com/followceleb.cms?alias=texting,Spine,Smartphone,Kenneth Hansraj,back pain

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22.10 | 0 komentar | Read More

Nanobodies to help out in boosting immunity

Written By Unknown on Sabtu, 08 November 2014 | 22.10

IANS | Nov 3, 2014, 02.39PM IST

Researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Page 1 of 4

NEW YORK: Targeting difficult-to-reach areas affected by disease could become a lot easier as researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Nanobodies could be much more efficient than antibodies in attacking diseased cells, but scientist have so far lacked an efficient way of identifying the nanobodies, which are more closely tuned to their targets.

"Nanobodies have tremendous potential as versatile and accessible alternatives to conventional antibodies, but unfortunately current techniques present a bottleneck to meeting the demand for them," said study author Michael Rout from the Rockefeller University in the US.

"We hope that our system will make high-affinity nanobodies more available, and open up many new possible uses for them," Rout added.

The study was conducted using llamas. They were injected with foreign proteins.

"The key was to figure out a relatively fast way of determining the genetic sequences of the antibodies that bind to the targets with the greatest affinity. Up until now obtaining these high-affinity sequences has been something of a holy grail," said Brian Chait, professor at the Rockefeller University.

"Once those sequences are obtained, it is easy to engineer bacteria to mass produce the antibodies," Chait added.

The researchers determined partial sequences of the amino acids that made up the protein of the nanobodies with a technique known as mass spectrometry.

Using a computer algorithm called 'llama magic', the researchers matched the composition of the highest affinity nanobody with the original genetic sequence.

The study appeared in the journal Nature Methods.

Article continues

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22.10 | 0 komentar | Read More

Scientists see mechanism for spontaneous HIV 'cure'

PARIS: French scientists said on Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS.

Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms.

The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said.

The change appeared to be linked to increased activity of a common enzyme named APOBEC, they theorized.

The "apparent spontaneous cure" throws up an intriguing avenue for drug engineers, the team said in a statement.

"The work opens up therapeutic avenues for a cure, using or stimulating this enzyme, and avenues for identifying individuals among newly-infected patients who have a chance of a spontaneous cure."

The work, published in the journal Clinical Microbiology and Infection, was carried out by scientists at France's Institute of Health and Medical Research (Inserm).

HIV replicates by invading human CD4 immune cells, which it reprogrammes to become virus factories.

A rare group of people — fewer than one per cent of those infected — are naturally able to rein in viral replication and keep the virus at clinically undetectable levels.

They are known as "elite controllers", but the mechanism by which they keep the virus at bay remains a mystery.

The French group looked at two such individuals, a 57-year-old man diagnosed HIV-positive in 1985, and a 23-year-old diagnosed in 2011, and sequenced their virus genomes.

Though they remained infected, standard tests could not detect the virus in their blood.

The team found that in both cases, the virus was unable to replicate in immune cells due to mutations in its genetic code.

The researchers suggested spontaneous evolution between humans and the virus, a process called "endogenisation" that is believed to have neutralized other viruses in humans in the past.

A similar process has been witnessed in a population of koalas that has integrated an AIDS-like virus into their genes, neutralized it, and were passing resistance on to their offspring.

"We propose that HIV cure may occur through HIV endogenisation in humans," the team wrote.

"These findings suggest that without therapeutic and prophylactic strategies, after several decades of HIV/host integrations and millions of deaths, it is likely that a few individuals might have endogenised and neutralized the virus and transmitted it to their progeny," they added.

"We believe that the persistence of HIV DNA can lead to cure, and protection, from HIV."

The approach hitherto has been the opposite: to try and clear all traces of HIV from human cells and from cell reservoirs where they hide.

"We suggest that persistence of integrated HIV DNA is not a barrier, but on the contrary, may be a prerequisite to HIV cure," said the study authors.

"We propose a new vision of HIV cure through integration, inactivation and potential endogenisation of a viral genome into the human genome."

The team said they did not believe the two patients were unique or that the phenomenon was new.

And they called for "massive sequencing" of human DNA, particularly from Africans who had been exposed to HIV for longest, to find further proof.

Only one person is thought to have ever been cured of HIV: Timothy Ray Brown who had bone marrow transplants as a treatment for leukaemia, from a donor with resistance to HIV.

A baby given anti-AIDS drugs immediately after birth for 18 months, was at first also thought to have been cured, but the virus later came back.


22.10 | 0 komentar | Read More

Spooky science: Ghosts 'created' in Swiss lab

LONDON: In a first, Swiss researchers have succeeded in recreating a ghost illusion in the laboratory.

Patients suffering from neurological or psychiatric conditions have often reported feeling a strange "presence" that is felt but unseen, akin to a guardian angel or a demon.

Researcher Olaf Blanke's team at Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland was able to recreate the illusion of a similar presence in the laboratory and provide a simple explanation.

They showed that the "feeling of a presence" actually results from an alteration of sensorimotor brain signals, which are involved in generating self-awareness by integrating information from our movements and our body's position in space.

Blanke's team interfered with the sensorimotor input of participants in such a way that their brains no longer identified such signals as belonging to their own body, but instead interpreted them as those of someone else.

The researchers first analysed the brains of 12 patients with neurological disorders - mostly epilepsy - who have experienced this kind of "apparition."

MRI analysis of the patients's brains unveiled interference with three cortical regions: the insular cortex, parietal-frontal cortex, and the temporo-parietal cortex.

These three areas are involved in self-awareness, movement, and the sense of position in space (proprioception).

They contribute to multisensory signal processing, which is important for the perception of one's own body.

The scientists then carried out a "dissonance" experiment in which blindfolded participants performed movements with their hand in front of their body.

Behind them, a robotic device reproduced their movements, touching them on the back in real time. The result was a kind of spatial discrepancy, but because of the synchronised movement of the robot, the participant's brain was able to adapt and correct for it.

Next, the neuroscientists introduced a temporal delay between the participant's movement and the robot's touch.

Under these asynchronous conditions, distorting temporal and spatial perception, the researchers were able to recreate the ghost illusion.

The participants were unaware of the experiment's purpose. After about three minutes of the delayed touching, the researchers asked them what they felt.

Instinctively, several subjects reported a strong "feeling of a presence," even counting up to four "ghosts" where none existed.

"For some, the feeling was even so strong that they asked to stop the experiment," said Giulio Rognini, who led the study.

"Our experiment induced the sensation of a foreign presence in the laboratory for the first time. It shows that it can arise under normal conditions, simply through conflicting sensory-motor signals," Blanke added.

(The research was published in the journal Current Biology.)

http://timesofindia.indiatimes.com/followceleb.cms?alias=Swiss researchers,Ghosts 'created' in Swiss lab

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22.10 | 0 komentar | Read More

Nanobodies to help out in boosting immunity

Written By Unknown on Jumat, 07 November 2014 | 22.10

IANS | Nov 3, 2014, 02.39PM IST

Researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Page 1 of 4

NEW YORK: Targeting difficult-to-reach areas affected by disease could become a lot easier as researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Nanobodies could be much more efficient than antibodies in attacking diseased cells, but scientist have so far lacked an efficient way of identifying the nanobodies, which are more closely tuned to their targets.

"Nanobodies have tremendous potential as versatile and accessible alternatives to conventional antibodies, but unfortunately current techniques present a bottleneck to meeting the demand for them," said study author Michael Rout from the Rockefeller University in the US.

"We hope that our system will make high-affinity nanobodies more available, and open up many new possible uses for them," Rout added.

The study was conducted using llamas. They were injected with foreign proteins.

"The key was to figure out a relatively fast way of determining the genetic sequences of the antibodies that bind to the targets with the greatest affinity. Up until now obtaining these high-affinity sequences has been something of a holy grail," said Brian Chait, professor at the Rockefeller University.

"Once those sequences are obtained, it is easy to engineer bacteria to mass produce the antibodies," Chait added.

The researchers determined partial sequences of the amino acids that made up the protein of the nanobodies with a technique known as mass spectrometry.

Using a computer algorithm called 'llama magic', the researchers matched the composition of the highest affinity nanobody with the original genetic sequence.

The study appeared in the journal Nature Methods.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

Page 1 of 4

MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Scientists see mechanism for spontaneous HIV 'cure'

PARIS: French scientists said on Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS.

Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms.

The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said.

The change appeared to be linked to increased activity of a common enzyme named APOBEC, they theorized.

The "apparent spontaneous cure" throws up an intriguing avenue for drug engineers, the team said in a statement.

"The work opens up therapeutic avenues for a cure, using or stimulating this enzyme, and avenues for identifying individuals among newly-infected patients who have a chance of a spontaneous cure."

The work, published in the journal Clinical Microbiology and Infection, was carried out by scientists at France's Institute of Health and Medical Research (Inserm).

HIV replicates by invading human CD4 immune cells, which it reprogrammes to become virus factories.

A rare group of people — fewer than one per cent of those infected — are naturally able to rein in viral replication and keep the virus at clinically undetectable levels.

They are known as "elite controllers", but the mechanism by which they keep the virus at bay remains a mystery.

The French group looked at two such individuals, a 57-year-old man diagnosed HIV-positive in 1985, and a 23-year-old diagnosed in 2011, and sequenced their virus genomes.

Though they remained infected, standard tests could not detect the virus in their blood.

The team found that in both cases, the virus was unable to replicate in immune cells due to mutations in its genetic code.

The researchers suggested spontaneous evolution between humans and the virus, a process called "endogenisation" that is believed to have neutralized other viruses in humans in the past.

A similar process has been witnessed in a population of koalas that has integrated an AIDS-like virus into their genes, neutralized it, and were passing resistance on to their offspring.

"We propose that HIV cure may occur through HIV endogenisation in humans," the team wrote.

"These findings suggest that without therapeutic and prophylactic strategies, after several decades of HIV/host integrations and millions of deaths, it is likely that a few individuals might have endogenised and neutralized the virus and transmitted it to their progeny," they added.

"We believe that the persistence of HIV DNA can lead to cure, and protection, from HIV."

The approach hitherto has been the opposite: to try and clear all traces of HIV from human cells and from cell reservoirs where they hide.

"We suggest that persistence of integrated HIV DNA is not a barrier, but on the contrary, may be a prerequisite to HIV cure," said the study authors.

"We propose a new vision of HIV cure through integration, inactivation and potential endogenisation of a viral genome into the human genome."

The team said they did not believe the two patients were unique or that the phenomenon was new.

And they called for "massive sequencing" of human DNA, particularly from Africans who had been exposed to HIV for longest, to find further proof.

Only one person is thought to have ever been cured of HIV: Timothy Ray Brown who had bone marrow transplants as a treatment for leukaemia, from a donor with resistance to HIV.

A baby given anti-AIDS drugs immediately after birth for 18 months, was at first also thought to have been cured, but the virus later came back.


22.10 | 0 komentar | Read More

Nanobodies to help out in boosting immunity

Written By Unknown on Kamis, 06 November 2014 | 22.10

IANS | Nov 3, 2014, 02.39PM IST

Researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Page 1 of 4

NEW YORK: Targeting difficult-to-reach areas affected by disease could become a lot easier as researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Nanobodies could be much more efficient than antibodies in attacking diseased cells, but scientist have so far lacked an efficient way of identifying the nanobodies, which are more closely tuned to their targets.

"Nanobodies have tremendous potential as versatile and accessible alternatives to conventional antibodies, but unfortunately current techniques present a bottleneck to meeting the demand for them," said study author Michael Rout from the Rockefeller University in the US.

"We hope that our system will make high-affinity nanobodies more available, and open up many new possible uses for them," Rout added.

The study was conducted using llamas. They were injected with foreign proteins.

"The key was to figure out a relatively fast way of determining the genetic sequences of the antibodies that bind to the targets with the greatest affinity. Up until now obtaining these high-affinity sequences has been something of a holy grail," said Brian Chait, professor at the Rockefeller University.

"Once those sequences are obtained, it is easy to engineer bacteria to mass produce the antibodies," Chait added.

The researchers determined partial sequences of the amino acids that made up the protein of the nanobodies with a technique known as mass spectrometry.

Using a computer algorithm called 'llama magic', the researchers matched the composition of the highest affinity nanobody with the original genetic sequence.

The study appeared in the journal Nature Methods.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

Page 1 of 4

MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Scientists see mechanism for spontaneous HIV 'cure'

PARIS: French scientists said on Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS.

Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms.

The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said.

The change appeared to be linked to increased activity of a common enzyme named APOBEC, they theorized.

The "apparent spontaneous cure" throws up an intriguing avenue for drug engineers, the team said in a statement.

"The work opens up therapeutic avenues for a cure, using or stimulating this enzyme, and avenues for identifying individuals among newly-infected patients who have a chance of a spontaneous cure."

The work, published in the journal Clinical Microbiology and Infection, was carried out by scientists at France's Institute of Health and Medical Research (Inserm).

HIV replicates by invading human CD4 immune cells, which it reprogrammes to become virus factories.

A rare group of people — fewer than one per cent of those infected — are naturally able to rein in viral replication and keep the virus at clinically undetectable levels.

They are known as "elite controllers", but the mechanism by which they keep the virus at bay remains a mystery.

The French group looked at two such individuals, a 57-year-old man diagnosed HIV-positive in 1985, and a 23-year-old diagnosed in 2011, and sequenced their virus genomes.

Though they remained infected, standard tests could not detect the virus in their blood.

The team found that in both cases, the virus was unable to replicate in immune cells due to mutations in its genetic code.

The researchers suggested spontaneous evolution between humans and the virus, a process called "endogenisation" that is believed to have neutralized other viruses in humans in the past.

A similar process has been witnessed in a population of koalas that has integrated an AIDS-like virus into their genes, neutralized it, and were passing resistance on to their offspring.

"We propose that HIV cure may occur through HIV endogenisation in humans," the team wrote.

"These findings suggest that without therapeutic and prophylactic strategies, after several decades of HIV/host integrations and millions of deaths, it is likely that a few individuals might have endogenised and neutralized the virus and transmitted it to their progeny," they added.

"We believe that the persistence of HIV DNA can lead to cure, and protection, from HIV."

The approach hitherto has been the opposite: to try and clear all traces of HIV from human cells and from cell reservoirs where they hide.

"We suggest that persistence of integrated HIV DNA is not a barrier, but on the contrary, may be a prerequisite to HIV cure," said the study authors.

"We propose a new vision of HIV cure through integration, inactivation and potential endogenisation of a viral genome into the human genome."

The team said they did not believe the two patients were unique or that the phenomenon was new.

And they called for "massive sequencing" of human DNA, particularly from Africans who had been exposed to HIV for longest, to find further proof.

Only one person is thought to have ever been cured of HIV: Timothy Ray Brown who had bone marrow transplants as a treatment for leukaemia, from a donor with resistance to HIV.

A baby given anti-AIDS drugs immediately after birth for 18 months, was at first also thought to have been cured, but the virus later came back.


22.10 | 0 komentar | Read More

Nanobodies to help out in boosting immunity

Written By Unknown on Rabu, 05 November 2014 | 22.10

IANS | Nov 3, 2014, 02.39PM IST

Researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Page 1 of 4

NEW YORK: Targeting difficult-to-reach areas affected by disease could become a lot easier as researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Nanobodies could be much more efficient than antibodies in attacking diseased cells, but scientist have so far lacked an efficient way of identifying the nanobodies, which are more closely tuned to their targets.

"Nanobodies have tremendous potential as versatile and accessible alternatives to conventional antibodies, but unfortunately current techniques present a bottleneck to meeting the demand for them," said study author Michael Rout from the Rockefeller University in the US.

"We hope that our system will make high-affinity nanobodies more available, and open up many new possible uses for them," Rout added.

The study was conducted using llamas. They were injected with foreign proteins.

"The key was to figure out a relatively fast way of determining the genetic sequences of the antibodies that bind to the targets with the greatest affinity. Up until now obtaining these high-affinity sequences has been something of a holy grail," said Brian Chait, professor at the Rockefeller University.

"Once those sequences are obtained, it is easy to engineer bacteria to mass produce the antibodies," Chait added.

The researchers determined partial sequences of the amino acids that made up the protein of the nanobodies with a technique known as mass spectrometry.

Using a computer algorithm called 'llama magic', the researchers matched the composition of the highest affinity nanobody with the original genetic sequence.

The study appeared in the journal Nature Methods.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

Page 1 of 4

MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


22.10 | 0 komentar | Read More

Scientists see mechanism for spontaneous HIV 'cure'

PARIS: French scientists said on Tuesday they had found the genetic mechanism by which two HIV-infected men may have experienced a "spontaneous cure", and said it offered a new strategy in the fight against AIDS.

Both men were infected by the human immunodeficiency virus (HIV), one of them 30 years ago, but never developed AIDS symptoms.

The AIDS-causing virus remained in their immune cells but was inactivated because its genetic code had been altered, the scientists said.

The change appeared to be linked to increased activity of a common enzyme named APOBEC, they theorized.

The "apparent spontaneous cure" throws up an intriguing avenue for drug engineers, the team said in a statement.

"The work opens up therapeutic avenues for a cure, using or stimulating this enzyme, and avenues for identifying individuals among newly-infected patients who have a chance of a spontaneous cure."

The work, published in the journal Clinical Microbiology and Infection, was carried out by scientists at France's Institute of Health and Medical Research (Inserm).

HIV replicates by invading human CD4 immune cells, which it reprogrammes to become virus factories.

A rare group of people — fewer than one per cent of those infected — are naturally able to rein in viral replication and keep the virus at clinically undetectable levels.

They are known as "elite controllers", but the mechanism by which they keep the virus at bay remains a mystery.

The French group looked at two such individuals, a 57-year-old man diagnosed HIV-positive in 1985, and a 23-year-old diagnosed in 2011, and sequenced their virus genomes.

Though they remained infected, standard tests could not detect the virus in their blood.

The team found that in both cases, the virus was unable to replicate in immune cells due to mutations in its genetic code.

The researchers suggested spontaneous evolution between humans and the virus, a process called "endogenisation" that is believed to have neutralized other viruses in humans in the past.

A similar process has been witnessed in a population of koalas that has integrated an AIDS-like virus into their genes, neutralized it, and were passing resistance on to their offspring.

"We propose that HIV cure may occur through HIV endogenisation in humans," the team wrote.

"These findings suggest that without therapeutic and prophylactic strategies, after several decades of HIV/host integrations and millions of deaths, it is likely that a few individuals might have endogenised and neutralized the virus and transmitted it to their progeny," they added.

"We believe that the persistence of HIV DNA can lead to cure, and protection, from HIV."

The approach hitherto has been the opposite: to try and clear all traces of HIV from human cells and from cell reservoirs where they hide.

"We suggest that persistence of integrated HIV DNA is not a barrier, but on the contrary, may be a prerequisite to HIV cure," said the study authors.

"We propose a new vision of HIV cure through integration, inactivation and potential endogenisation of a viral genome into the human genome."

The team said they did not believe the two patients were unique or that the phenomenon was new.

And they called for "massive sequencing" of human DNA, particularly from Africans who had been exposed to HIV for longest, to find further proof.

Only one person is thought to have ever been cured of HIV: Timothy Ray Brown who had bone marrow transplants as a treatment for leukaemia, from a donor with resistance to HIV.

A baby given anti-AIDS drugs immediately after birth for 18 months, was at first also thought to have been cured, but the virus later came back.

http://timesofindia.indiatimes.com/followceleb.cms?alias=HIV cure,French scientists,Clinical Microbiology and Infection,aids

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Sweden to get world’s first remote-controlled airport

Written By Unknown on Senin, 03 November 2014 | 22.10

ORNSKOLDSVIK (SWEDEN ) : On a clear day, Per Granquist cannot see forever. But from his perch inside the airport control tower here, he does have an unobstructed view of the future.

The big picture is provided from a 33-foot mast where a gray turret holds an array of digital video cameras, communications antennas, sensors and microphones — a setup that resembles a cross between a space-age dovecote and a prison guard tower. The system is meant to collect and integrate information of the sort that Mr. Granquist, 40, has been providing with his own eyes and ears as an air traffic controller for the last 17 years at this small airport in northern Sweden.

The information from this array, though, is being sent elsewhere — beamed by fiber-optic cable to a windowless room of another airport, 100 miles south, in the slightly larger town of Sundsvall.

The system is still in test mode, but the rest of the global commercial aviation industry is watching closely. Early next year, Mr. Granquist and a handful of his colleagues expect to move to Sundsvall. And from there, they will begin "virtually" guiding the half-dozen or so daily flights in and out of Ornskoldsvik.

Ornskoldsvik is about to become the world's first remotely controlled airport.

"At first it seemed a bit weird," Mr. Granquist said of his training on the new system.

In Sundsvall, instead of surveying the airport through plate-glass windows, he will sit before a semicircular wall of more than a dozen 55-inch liquid-crystal displays.

"But after two weeks," Mr. Granquist added, "it really feels no different from sitting here."

Carved from an Arctic pine forest along Sweden's fjord-studded eastern coast, Ornskoldsvik might seem an unlikely setting for a potential aviation revolution. But over the last several years, officials from dozens of countries have made their way down the airport's rutted gravel road and past the yellow moose-crossing signs to get a firsthand look at technology that many expect will eventually transform the way air traffic is managed worldwide.

It is a concept that experts say has uses not only for the world's out-of-the way places but could also enhance efficiency and safety at sprawling urban airports where increasing air traffic places ever greater demands on human controllers.

"I have little doubt that this is the next big thing for our industry," said Paul Jones, operations manager at NATS, which provides air navigation services at Heathrow and a dozen other British airports.

He is among those who have seen the Swedish setup firsthand.

"I do think one day it could replace traditional visual control towers almost completely," Mr. Jones said.

It is no accident that the idea for a remote-controlled airport emerged from Sweden, whose northern regions are thinly populated and poorly served by rail or other transportation alternatives. Much like Alaska and vast swaths of northern Canada, Scandinavia is dotted with dozens of small airports that provide vital connections to the outside world.

While many of the world's remote communities are so tiny as to rely on small private planes whose pilots coordinate their own takeoffs and landings by radio, towns like Ornskoldsvik — population 55,000 — are just big enough to justify minimal scheduled airline services and a control tower. Yet with just a handful of takeoffs and landings most days, air traffic controllers at such airports often spend more of their time monitoring the weather or filling out paperwork than actually guiding planes.

"It doesn't really make economic or even social sense to station a fully qualified air traffic controller in some of these places," said Erik Backman, director of operations at LFV, Sweden's state-owned air navigation service provider.

Full-time controllers in Sweden average about $77,000 a year in pay, he said, a cost that rises to more than $140,000, once social security and other employee charges are included. There are also expenses for maintaining a building for use by human controllers. For the 28 civilian and military airports that LFV serves — several of them, like Ornskoldsvik, lose money — air traffic control represents a large part of their operating costs.

That is why LFV began exploring the idea of pooling controllers at a single location, to guide flights remotely. In 2006, the agency invited the Swedish aeronautics and technology group Saab to develop a prototype that could be operated with minimal additional training by licensed controllers as well as meet international safety requirements. The system Saab developed was installed at both Ornskoldsvik and Sundsvall airports in 2012 and it was expected to receive certification from Swedish regulators by the end of this week.

To guard against a remote-control airport's being hijacked by hackers, the data transmitted between the camera tower and the remote control center is scrambled using dedicated hardware and encryption software, said Anders Carp, a Saab vice president in charge of traffic management systems. As an added layer of security, he said, Saab also uses an algorithm to verify that images have not been tampered with en route.

Mikael Henriksson has been at the fore of LFV's push into the future. An air traffic controller for 40 years, Mr. Henriksson, 59, has worked at dozens of civilian and military airports in Sweden and abroad, including a few harrowing stints in the war zones of Iraq. His job now is helping controllers like Mr. Granquist make the leap to remote tower technology, which unlike transitioning from being an airplane pilot to a drone operator, largely relies on an identical set of skills.

"Controllers are already spending most of their time looking at a screen instead of out a window," Mr. Henriksson said.

On a recent day at the remote control center in Sundsvall, Mr. Henriksson put the cameras in Ornskoldsvik through their paces. With the tap of a stylus on a sleek glass panel, the arc of display panels flickered to life, presenting a crisp 360-degree panorama of the Ornskoldsvik runway.

As passengers boarded a Stockholm-bound turboprop on the tarmac, a flock of blackbirds flitted over the projected airfield, then disappeared into the trees, which swayed in the gentle breeze. A truck rolling slowly past a hangar was automatically highlighted by a red rectangle that followed its movement across the screens. Mr. Henriksson clicked to activate one of two robotic zoom cameras, opening a new window that functioned as virtual binoculars.

When the plane took off, a few minutes later, the hum of its engines passed from right to left through the room's speakers, in perfect surround sound.

Mr. Carp, of Saab, explained that the system could be equipped with optional enhancements like infrared or night-vision lenses and 3-D-augmented reality overlays. Such features could come in particularly handy in places like Scandinavia, where frequent snowstorms and long winter nights are particularly challenging to air controllers. A built-in recording function allows airports to store and replay video and data for training purposes — or to aid investigators in the event of an accident.

Officials at larger airports are also intrigued by the possibility of using remote camera technology to complement traditional control towers — either to give human controllers a clearer view of parts of the airport that might be obstructed by other buildings, or to serve as a contingency in the event of extreme weather, a disaster or even a terrorist attack.

A few major international airports already have emergency backup centers where a team of controllers can direct a reduced number of flights remotely, relying on radar and radio communications. Heathrow, for example, set up such a site in 2009, in a building near the airport that Mr. Jones of NATS said had never been deployed but was capable of operating at 80 percent capacity in the event the airport's main control towers were disabled by a fire or a power failure.

"But it doesn't have windows," Mr. Jones said of the Heathrow site. Installing a remote-tower system with cameras and video screens, he said, would — virtually, at least - "put the windows back in" and enable the airport, Europe's busiest, to operate at close to full capacity in an emergency.

Back in Ornskoldsvik, Mr. Granquist most days now works his nine-hour shift in solitude, with only an occasional visit from Robert Gyllroth, the airport manager, who sometimes asks him to pitch in with other airport tasks, like manning the tiny duty-free shop.

Three years ago, when he first learned of the plan to operate Ornskoldsvik's tower remotely, Mr. Granquist was upset at the prospect of having to move his family to Sundsvall. But his reluctance has since turned to impatience — and excitement at the career possibilities that remote technology might open for him at other, larger airports.

"It will also be nice," Mr. Granquist said as he padded in stocking feet to adjust a window blind against the setting sun, "to have some colleagues."


22.10 | 0 komentar | Read More

Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

Page 1 of 4

MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

Article continues

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Nanobodies to help out in boosting immunity

NEW YORK: Targeting difficult-to-reach areas affected by disease could become a lot easier as researchers have developed a new system to make nanobodies, the efficient tiny cousins of antibodies, the defensive proteins deployed by the immune system, more accessible.

Nanobodies could be much more efficient than antibodies in attacking diseased cells, but scientist have so far lacked an efficient way of identifying the nanobodies, which are more closely tuned to their targets.

"Nanobodies have tremendous potential as versatile and accessible alternatives to conventional antibodies, but unfortunately current techniques present a bottleneck to meeting the demand for them," said study author Michael Rout from the Rockefeller University in the US.

"We hope that our system will make high-affinity nanobodies more available, and open up many new possible uses for them," Rout added.

The study was conducted using llamas. They were injected with foreign proteins.

"The key was to figure out a relatively fast way of determining the genetic sequences of the antibodies that bind to the targets with the greatest affinity. Up until now obtaining these high-affinity sequences has been something of a holy grail," said Brian Chait, professor at the Rockefeller University.

"Once those sequences are obtained, it is easy to engineer bacteria to mass produce the antibodies," Chait added.

The researchers determined partial sequences of the amino acids that made up the protein of the nanobodies with a technique known as mass spectrometry.

Using a computer algorithm called 'llama magic', the researchers matched the composition of the highest affinity nanobody with the original genetic sequence.

The study appeared in the journal Nature Methods.

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Warming climate restructuring bird population

Written By Unknown on Minggu, 02 November 2014 | 22.10

IANS | Oct 18, 2014, 11.05PM IST

Birds typically found in more southerly regions are gradually pushing north.

Page 1 of 4

WASHINGTON: Driven by a warming climate, birds typically found in more southerly regions are gradually pushing north, restructuring the communities of birds that spend their winter in northern latitudes, research has found.

Over the past two decades, the resident communities of birds that attend eastern North America's backyard bird feeders in winter have quietly been remade, the findings showed.

The readily familiar species include cardinals, chipping sparrows and Carolina wrens.

"Fifty years ago, cardinals were rare in the north-eastern United States. Carolina wrens even more so," explained study co-author Benjamin Zuckerberg from the University of Wisconsin-Madison in the US.

These birds and other warm-adapted species have greatly expanded their wintering range in a warmer world, a change that may have untold consequences for North American ecosystems, the authors noted.

The researchers measured the changes over time, resulting in the abundance of 38 bird species at feeders in eastern North America.

They specifically looked at the influence of changes in winter minimum temperature over a 22-year period on the flocks of birds that gather at backyard feeding stations.

"We conclude that a shifting winter climate has provided an opportunity for smaller, southerly distributed species to colonise new regions and promote the formation of unique winter bird assemblages throughout eastern North America," the authors wrote.

Climate models predict even warmer temperatures occurring over the next 100 years, with seasonal climate effects being the most pronounced in northern regions of the world.

Article continues

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22.10 | 0 komentar | Read More

Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

Page 1 of 4

MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

Article continues

Stay updated on the go with The Times of India's mobile apps. Click here to download it for your device.


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Sweden to get world’s first remote-controlled airport

ORNSKOLDSVIK (SWEDEN ) : On a clear day, Per Granquist cannot see forever. But from his perch inside the airport control tower here, he does have an unobstructed view of the future.

The big picture is provided from a 33-foot mast where a gray turret holds an array of digital video cameras, communications antennas, sensors and microphones — a setup that resembles a cross between a space-age dovecote and a prison guard tower. The system is meant to collect and integrate information of the sort that Mr. Granquist, 40, has been providing with his own eyes and ears as an air traffic controller for the last 17 years at this small airport in northern Sweden.

The information from this array, though, is being sent elsewhere — beamed by fiber-optic cable to a windowless room of another airport, 100 miles south, in the slightly larger town of Sundsvall.

The system is still in test mode, but the rest of the global commercial aviation industry is watching closely. Early next year, Mr. Granquist and a handful of his colleagues expect to move to Sundsvall. And from there, they will begin "virtually" guiding the half-dozen or so daily flights in and out of Ornskoldsvik.

Ornskoldsvik is about to become the world's first remotely controlled airport.

"At first it seemed a bit weird," Mr. Granquist said of his training on the new system.

In Sundsvall, instead of surveying the airport through plate-glass windows, he will sit before a semicircular wall of more than a dozen 55-inch liquid-crystal displays.

"But after two weeks," Mr. Granquist added, "it really feels no different from sitting here."

Carved from an Arctic pine forest along Sweden's fjord-studded eastern coast, Ornskoldsvik might seem an unlikely setting for a potential aviation revolution. But over the last several years, officials from dozens of countries have made their way down the airport's rutted gravel road and past the yellow moose-crossing signs to get a firsthand look at technology that many expect will eventually transform the way air traffic is managed worldwide.

It is a concept that experts say has uses not only for the world's out-of-the way places but could also enhance efficiency and safety at sprawling urban airports where increasing air traffic places ever greater demands on human controllers.

"I have little doubt that this is the next big thing for our industry," said Paul Jones, operations manager at NATS, which provides air navigation services at Heathrow and a dozen other British airports.

He is among those who have seen the Swedish setup firsthand.

"I do think one day it could replace traditional visual control towers almost completely," Mr. Jones said.

It is no accident that the idea for a remote-controlled airport emerged from Sweden, whose northern regions are thinly populated and poorly served by rail or other transportation alternatives. Much like Alaska and vast swaths of northern Canada, Scandinavia is dotted with dozens of small airports that provide vital connections to the outside world.

While many of the world's remote communities are so tiny as to rely on small private planes whose pilots coordinate their own takeoffs and landings by radio, towns like Ornskoldsvik — population 55,000 — are just big enough to justify minimal scheduled airline services and a control tower. Yet with just a handful of takeoffs and landings most days, air traffic controllers at such airports often spend more of their time monitoring the weather or filling out paperwork than actually guiding planes.

"It doesn't really make economic or even social sense to station a fully qualified air traffic controller in some of these places," said Erik Backman, director of operations at LFV, Sweden's state-owned air navigation service provider.

Full-time controllers in Sweden average about $77,000 a year in pay, he said, a cost that rises to more than $140,000, once social security and other employee charges are included. There are also expenses for maintaining a building for use by human controllers. For the 28 civilian and military airports that LFV serves — several of them, like Ornskoldsvik, lose money — air traffic control represents a large part of their operating costs.

That is why LFV began exploring the idea of pooling controllers at a single location, to guide flights remotely. In 2006, the agency invited the Swedish aeronautics and technology group Saab to develop a prototype that could be operated with minimal additional training by licensed controllers as well as meet international safety requirements. The system Saab developed was installed at both Ornskoldsvik and Sundsvall airports in 2012 and it was expected to receive certification from Swedish regulators by the end of this week.

To guard against a remote-control airport's being hijacked by hackers, the data transmitted between the camera tower and the remote control center is scrambled using dedicated hardware and encryption software, said Anders Carp, a Saab vice president in charge of traffic management systems. As an added layer of security, he said, Saab also uses an algorithm to verify that images have not been tampered with en route.

Mikael Henriksson has been at the fore of LFV's push into the future. An air traffic controller for 40 years, Mr. Henriksson, 59, has worked at dozens of civilian and military airports in Sweden and abroad, including a few harrowing stints in the war zones of Iraq. His job now is helping controllers like Mr. Granquist make the leap to remote tower technology, which unlike transitioning from being an airplane pilot to a drone operator, largely relies on an identical set of skills.

"Controllers are already spending most of their time looking at a screen instead of out a window," Mr. Henriksson said.

On a recent day at the remote control center in Sundsvall, Mr. Henriksson put the cameras in Ornskoldsvik through their paces. With the tap of a stylus on a sleek glass panel, the arc of display panels flickered to life, presenting a crisp 360-degree panorama of the Ornskoldsvik runway.

As passengers boarded a Stockholm-bound turboprop on the tarmac, a flock of blackbirds flitted over the projected airfield, then disappeared into the trees, which swayed in the gentle breeze. A truck rolling slowly past a hangar was automatically highlighted by a red rectangle that followed its movement across the screens. Mr. Henriksson clicked to activate one of two robotic zoom cameras, opening a new window that functioned as virtual binoculars.

When the plane took off, a few minutes later, the hum of its engines passed from right to left through the room's speakers, in perfect surround sound.

Mr. Carp, of Saab, explained that the system could be equipped with optional enhancements like infrared or night-vision lenses and 3-D-augmented reality overlays. Such features could come in particularly handy in places like Scandinavia, where frequent snowstorms and long winter nights are particularly challenging to air controllers. A built-in recording function allows airports to store and replay video and data for training purposes — or to aid investigators in the event of an accident.

Officials at larger airports are also intrigued by the possibility of using remote camera technology to complement traditional control towers — either to give human controllers a clearer view of parts of the airport that might be obstructed by other buildings, or to serve as a contingency in the event of extreme weather, a disaster or even a terrorist attack.

A few major international airports already have emergency backup centers where a team of controllers can direct a reduced number of flights remotely, relying on radar and radio communications. Heathrow, for example, set up such a site in 2009, in a building near the airport that Mr. Jones of NATS said had never been deployed but was capable of operating at 80 percent capacity in the event the airport's main control towers were disabled by a fire or a power failure.

"But it doesn't have windows," Mr. Jones said of the Heathrow site. Installing a remote-tower system with cameras and video screens, he said, would — virtually, at least - "put the windows back in" and enable the airport, Europe's busiest, to operate at close to full capacity in an emergency.

Back in Ornskoldsvik, Mr. Granquist most days now works his nine-hour shift in solitude, with only an occasional visit from Robert Gyllroth, the airport manager, who sometimes asks him to pitch in with other airport tasks, like manning the tiny duty-free shop.

Three years ago, when he first learned of the plan to operate Ornskoldsvik's tower remotely, Mr. Granquist was upset at the prospect of having to move his family to Sundsvall. But his reluctance has since turned to impatience — and excitement at the career possibilities that remote technology might open for him at other, larger airports.

"It will also be nice," Mr. Granquist said as he padded in stocking feet to adjust a window blind against the setting sun, "to have some colleagues."


22.10 | 0 komentar | Read More

Sweden to get world’s first remote-controlled airport

Written By Unknown on Sabtu, 01 November 2014 | 22.11

ORNSKOLDSVIK (SWEDEN ) : On a clear day, Per Granquist cannot see forever. But from his perch inside the airport control tower here, he does have an unobstructed view of the future.

The big picture is provided from a 33-foot mast where a gray turret holds an array of digital video cameras, communications antennas, sensors and microphones — a setup that resembles a cross between a space-age dovecote and a prison guard tower. The system is meant to collect and integrate information of the sort that Mr. Granquist, 40, has been providing with his own eyes and ears as an air traffic controller for the last 17 years at this small airport in northern Sweden.

The information from this array, though, is being sent elsewhere — beamed by fiber-optic cable to a windowless room of another airport, 100 miles south, in the slightly larger town of Sundsvall.

The system is still in test mode, but the rest of the global commercial aviation industry is watching closely. Early next year, Mr. Granquist and a handful of his colleagues expect to move to Sundsvall. And from there, they will begin "virtually" guiding the half-dozen or so daily flights in and out of Ornskoldsvik.

Ornskoldsvik is about to become the world's first remotely controlled airport.

"At first it seemed a bit weird," Mr. Granquist said of his training on the new system.

In Sundsvall, instead of surveying the airport through plate-glass windows, he will sit before a semicircular wall of more than a dozen 55-inch liquid-crystal displays.

"But after two weeks," Mr. Granquist added, "it really feels no different from sitting here."

Carved from an Arctic pine forest along Sweden's fjord-studded eastern coast, Ornskoldsvik might seem an unlikely setting for a potential aviation revolution. But over the last several years, officials from dozens of countries have made their way down the airport's rutted gravel road and past the yellow moose-crossing signs to get a firsthand look at technology that many expect will eventually transform the way air traffic is managed worldwide.

It is a concept that experts say has uses not only for the world's out-of-the way places but could also enhance efficiency and safety at sprawling urban airports where increasing air traffic places ever greater demands on human controllers.

"I have little doubt that this is the next big thing for our industry," said Paul Jones, operations manager at NATS, which provides air navigation services at Heathrow and a dozen other British airports.

He is among those who have seen the Swedish setup firsthand.

"I do think one day it could replace traditional visual control towers almost completely," Mr. Jones said.

It is no accident that the idea for a remote-controlled airport emerged from Sweden, whose northern regions are thinly populated and poorly served by rail or other transportation alternatives. Much like Alaska and vast swaths of northern Canada, Scandinavia is dotted with dozens of small airports that provide vital connections to the outside world.

While many of the world's remote communities are so tiny as to rely on small private planes whose pilots coordinate their own takeoffs and landings by radio, towns like Ornskoldsvik — population 55,000 — are just big enough to justify minimal scheduled airline services and a control tower. Yet with just a handful of takeoffs and landings most days, air traffic controllers at such airports often spend more of their time monitoring the weather or filling out paperwork than actually guiding planes.

"It doesn't really make economic or even social sense to station a fully qualified air traffic controller in some of these places," said Erik Backman, director of operations at LFV, Sweden's state-owned air navigation service provider.

Full-time controllers in Sweden average about $77,000 a year in pay, he said, a cost that rises to more than $140,000, once social security and other employee charges are included. There are also expenses for maintaining a building for use by human controllers. For the 28 civilian and military airports that LFV serves — several of them, like Ornskoldsvik, lose money — air traffic control represents a large part of their operating costs.

That is why LFV began exploring the idea of pooling controllers at a single location, to guide flights remotely. In 2006, the agency invited the Swedish aeronautics and technology group Saab to develop a prototype that could be operated with minimal additional training by licensed controllers as well as meet international safety requirements. The system Saab developed was installed at both Ornskoldsvik and Sundsvall airports in 2012 and it was expected to receive certification from Swedish regulators by the end of this week.

To guard against a remote-control airport's being hijacked by hackers, the data transmitted between the camera tower and the remote control center is scrambled using dedicated hardware and encryption software, said Anders Carp, a Saab vice president in charge of traffic management systems. As an added layer of security, he said, Saab also uses an algorithm to verify that images have not been tampered with en route.

Mikael Henriksson has been at the fore of LFV's push into the future. An air traffic controller for 40 years, Mr. Henriksson, 59, has worked at dozens of civilian and military airports in Sweden and abroad, including a few harrowing stints in the war zones of Iraq. His job now is helping controllers like Mr. Granquist make the leap to remote tower technology, which unlike transitioning from being an airplane pilot to a drone operator, largely relies on an identical set of skills.

"Controllers are already spending most of their time looking at a screen instead of out a window," Mr. Henriksson said.

On a recent day at the remote control center in Sundsvall, Mr. Henriksson put the cameras in Ornskoldsvik through their paces. With the tap of a stylus on a sleek glass panel, the arc of display panels flickered to life, presenting a crisp 360-degree panorama of the Ornskoldsvik runway.

As passengers boarded a Stockholm-bound turboprop on the tarmac, a flock of blackbirds flitted over the projected airfield, then disappeared into the trees, which swayed in the gentle breeze. A truck rolling slowly past a hangar was automatically highlighted by a red rectangle that followed its movement across the screens. Mr. Henriksson clicked to activate one of two robotic zoom cameras, opening a new window that functioned as virtual binoculars.

When the plane took off, a few minutes later, the hum of its engines passed from right to left through the room's speakers, in perfect surround sound.

Mr. Carp, of Saab, explained that the system could be equipped with optional enhancements like infrared or night-vision lenses and 3-D-augmented reality overlays. Such features could come in particularly handy in places like Scandinavia, where frequent snowstorms and long winter nights are particularly challenging to air controllers. A built-in recording function allows airports to store and replay video and data for training purposes — or to aid investigators in the event of an accident.

Officials at larger airports are also intrigued by the possibility of using remote camera technology to complement traditional control towers — either to give human controllers a clearer view of parts of the airport that might be obstructed by other buildings, or to serve as a contingency in the event of extreme weather, a disaster or even a terrorist attack.

A few major international airports already have emergency backup centers where a team of controllers can direct a reduced number of flights remotely, relying on radar and radio communications. Heathrow, for example, set up such a site in 2009, in a building near the airport that Mr. Jones of NATS said had never been deployed but was capable of operating at 80 percent capacity in the event the airport's main control towers were disabled by a fire or a power failure.

"But it doesn't have windows," Mr. Jones said of the Heathrow site. Installing a remote-tower system with cameras and video screens, he said, would — virtually, at least - "put the windows back in" and enable the airport, Europe's busiest, to operate at close to full capacity in an emergency.

Back in Ornskoldsvik, Mr. Granquist most days now works his nine-hour shift in solitude, with only an occasional visit from Robert Gyllroth, the airport manager, who sometimes asks him to pitch in with other airport tasks, like manning the tiny duty-free shop.

Three years ago, when he first learned of the plan to operate Ornskoldsvik's tower remotely, Mr. Granquist was upset at the prospect of having to move his family to Sundsvall. But his reluctance has since turned to impatience — and excitement at the career possibilities that remote technology might open for him at other, larger airports.

"It will also be nice," Mr. Granquist said as he padded in stocking feet to adjust a window blind against the setting sun, "to have some colleagues."


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Why pop stars live fast and die young

PTI | Oct 29, 2014, 05.57AM IST

<font size="2">The professor who conducted the study said that pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy. </font>

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MELBOURNE : It's long been said that pop stars live fast and die young, but a new Australian study has added scholarly credibility to the adage. Popular musicians in the US die up to 25 years earlier than the general population, with suicide rates among the performers between two and seven times greater, a "disturbing" new study has found.

Professor Dianna Kenny, from The University of Sydney, conducted a study of 12,665 performing pop musicians from all popular genres who died between 1950 and June this year. Out of the musicians studied, 11,478 were male.

The results of the study were "disturbing", according to Kenny.

Across the seven decades studied, popular musicians' lifespans were up to 25 years shorter than the comparable US population. Accidental death rates were between five and 10 times greater. Suicide rates were between two and seven times greater; and homicide rates were up to eight times greater than the US population. "This is clear evidence that all is not well in pop music land," Kenny said.

"The pop music 'scene' fails to provide boundaries and to model and expect acceptable behaviour. It actually does the reverse — it valorizes outrageous behaviour and the acting out of aggressive, sexual and destructive impulses that most of us dare only live out in fantasy," Kenny wrote in an article published by 'The Conversation'.

The music industry needs to consider these findings to discover ways of recognizing and assisting young musicians in distress, according to Kenny.

For the study, data on age, circumstances and manner of death were accessed from over 200 sources. The researcher also went to rapper death websites, Dead Punk Stars and similar sites for all popular music genres.

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Warming climate restructuring bird population

IANS | Oct 18, 2014, 11.05PM IST

Birds typically found in more southerly regions are gradually pushing north.

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WASHINGTON: Driven by a warming climate, birds typically found in more southerly regions are gradually pushing north, restructuring the communities of birds that spend their winter in northern latitudes, research has found.

Over the past two decades, the resident communities of birds that attend eastern North America's backyard bird feeders in winter have quietly been remade, the findings showed.

The readily familiar species include cardinals, chipping sparrows and Carolina wrens.

"Fifty years ago, cardinals were rare in the north-eastern United States. Carolina wrens even more so," explained study co-author Benjamin Zuckerberg from the University of Wisconsin-Madison in the US.

These birds and other warm-adapted species have greatly expanded their wintering range in a warmer world, a change that may have untold consequences for North American ecosystems, the authors noted.

The researchers measured the changes over time, resulting in the abundance of 38 bird species at feeders in eastern North America.

They specifically looked at the influence of changes in winter minimum temperature over a 22-year period on the flocks of birds that gather at backyard feeding stations.

"We conclude that a shifting winter climate has provided an opportunity for smaller, southerly distributed species to colonise new regions and promote the formation of unique winter bird assemblages throughout eastern North America," the authors wrote.

Climate models predict even warmer temperatures occurring over the next 100 years, with seasonal climate effects being the most pronounced in northern regions of the world.

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